The Generation Study
Babies born at the RUH to have the opportunity to receive genetic testing, as part of world-leading research study
If you have a baby at the RUH in 2026, you may be invited to take part in the Generation Study, a groundbreaking initiative led by Genomics England in partnership with the NHS.
The study, which is one of the world’s largest research studies of its kind, explores how whole genome sequencing could be used to screen newborns for over 200 rare but treatable conditions that usually appear in the first few years of life. The full list of conditions can be found on the Generation Study website.
By identifying these conditions at the earliest stage possible, instead of waiting until symptoms might appear, we can offer more timely treatment and the right support for families, helping children to live healthier lives.
With more than 25,000 babies already signed up across the country, families are seeing life-changing benefits. Now we’re proud to be bringing this study to the RUH, to support the health of the youngest members of our community.
What does this mean for families?
Taking part in the Generation Study is voluntary and free.
If you’re cared for by one of the RUH’s birthing teams during 2026, you may be asked about the Generation Study during your pregnancy. If you’re interested, you’ll have the chance to speak with a research midwife to help you decide whether to take part. We’ll also check in with you again shortly after birth.
If you consent, a blood sample will be taken (normally from the umbilical cord) and sent to a laboratory for whole genome sequencing. Results are usually shared with parents within 28 days if a condition is suspected, or within a few months if no conditions are suspected.
If a newborn is identified as having a treatable condition, further testing will take place to confirm the diagnosis. Families will receive ongoing support and treatment from the NHS.