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Blood Sciences

Blood Test Information

Dihydropyrimidine Dehydrogenase
(a.k.a DPD-5FU toxicity, DPD-DNA)
minimum sample volume required ~ 4ml

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Special instructions
Please send a random urine sample as well.
Sent away to St Thomas' Hospital, London

Reference range
See report or Contact Lab

Units
See report or contact Lab

Turnaround Time
21 days

Department: Biochemistry

Clinical Application
Dihydropyrimidine dehydrogenase (DPD) is the enzyme involved in the metabolism of uracil and thymine. Deficiency of this enzyme can lead to the life threatening toxicity following exposure to the chemotherapy drug 5-fluorouracil and Tegafur-uricil.

 
 

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