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Blood Sciences

Blood Test Information

minimum sample volume required ~ 4ml

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Test Code: CPE

Tube type: EDTA

Special instructions
Send separate Glucose (fluoride) sample.
Sample must be received in lab within 24 hours of collection.

Sent away to Royal Devon and Exeter NHS Foundation Trust

Reference range
370-1470 (For a healthy idividual with normal glucose measurment)


Linked to

Turnaround Time
10 days

Department: Biochemistry

Clinical Application
C-peptide is released at the time of endogenous insulin secretion. Discrepancy between c-peptide and insulin measurements can help in the differential diagnosis of hypoglycaemia (low c-peptide values seen in factitious exogenous insulin-induced disorder.

During a hypoglycaemic episode, a C-Peptide concentration greater than 300 pmol/L is inappropriately high. (C-peptide is considered supressed if less than 94 pmol/L). Indeterminate values i.e. 94-300 pmol/L require measurement of beta hydroxybutyrate to determine if hyperinsulinism is present.


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