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TTG
(a.k.a Tissue transglutaminase, Coeliac screen)
minimum sample volume required ~ 5ml
Test Code: TTG
Tube type: SST
Special instructions
Time limit for add on = 3 days
Interfering substances = none known
Reference range
<4
Units
IU/mL
Linked to
Endomysial antibodies (NDO)
Turnaround Time
14
days
Department: Immunology
Clinical Application
IgA ELISA used to screen for coeliac disease and some other gluten-sensitive conditions (such as dermatitis herpetiformis).
Please note, screening for coeliac disease should be undertaken whilst the patient is on a gluten containing diet.
Positive samples will be reflexed for confirmatory IgA anti-endomysial assay. If IgA TTG is below a set assay value, the sample will be checked for IgA deficiency. If the IgA result is <0.2g/L, an IgG anti-endomysial test will be performed.
If the TTG result is >40IU/mL, a repeat sample is recommend for IgA anti-endomysial testing.
Webpage updated: September 2024.
