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Autoimmune Profile
(a.k.a AIP, GPC, LKM, SMA, AMA)
minimum sample volume required ~ 5ml
Special instructions
Time limit for add on = 2days Interfering substances = none known
Minimum retesting interval
Test should not be repeated within 40 days
Further work will follow positive results if it is deemed appropriate, please contact lab for further information if necessary.
Reference range
neg
Linked to
AIP,SMA,AMA,GPC,LKM,ANA,Anti-Reticulin
Turnaround Time
7
days
Department: Immunology
Clinical Application
An indirect immunofluorescence assay (IFA) for the screening of:
ANA (antinuclear antibodies) - to aid diagnosis of connective tissue or rheumatoid diseases.
AMA (antimitochondrial antibodies) - association with primary biliary cirrhosis.
ASMA (anti-smooth muscle antibodies) - association with chronic active hepatitis.
GPC (gastric parietal cell antibodies) - association with pernicious anaemia.
LKM (liver/kidney microsomal antibodies) - associated with autoimmune hepatitis, hepatitis C and hepatitis associated with autoimmune polyglandular disease type 1.
