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Oestradiol
(a.k.a Estradiol, E2, 17-β Oestradiol)
minimum sample volume required ~ 5ml
Test Code: E2
Tube type: SST
Other acceptable tube types
Lithium heparin (pale green)
Special instructions
Cycle details required.
Time limit for add on
3 days post collection.
Reference range
<1 year: <200, 1-12 years: <80. Females >12 years: Follicular phase: 80 - 420, Mid-cycle: 120 – 1900, Luteal phase: 130 – 900, Peri- or post-menopausal: <110. Males >12 years: <150.
Units
pmol/L
Turnaround Time
1
day
Department: Biochemistry
Clinical Application
JCEM Endocrine Society consensus statement 2014 agreed that use should be limited until assay performance improved.
Oestradiol utility is limited to:
Fertility treatment
Endocrine clinic assessment of hypothalamic/pituitary failure
Investigation of precocious puberty
Adrenal tumours and/or gonadal dysgenesis
Transgender treatment
Rarely - HRT absorption with transdermal route (only via menopause/expert clinic)
Webpage updated: July 2026.
