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Pathology Departments Requesting & Reporting Blood Test Information Phlebotomy Guide Contact us
Blood Sciences

Blood Test Information

minimum sample volume required ~ 5ml

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Tube type: SST

Special instructions

Reference Range
0-6 months: 4 - 11
>6 months: 11 - 22

Sent away to University Hospital of Wales, Heath Park, Cardiff


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Turnaround Time
21 days

Department: Biochemistry

Clinical Application
Investigation of suspected Wilson's disease, e.g where ALT is persistently elevated. Use in conjunction with serum measurement of caeruloplasmin. Urine copper excretion may also need to be measured if serum copper/caeruloplasmin is abnormal or equivocal.

Acute inflammatory response causes gradual increase in copper concentration due to induction of caeruloplasmin synthesis. Consider appropriateness of request if CRP is significantly elevated (e.g. if CRP 100-200, there may be a 30% increase in serum copper concentration).
Copper results should be interpreted alongside albumin and CRP results.


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