17-OH Progesterone
minimum sample volume required ~ 5ml
Test Code: 17P
Tube type: SST
Special instructions
Blood spot also useable in some cases. Do not take within 48 hours of birth.
Sent away
to the Endocrine laboratory, Department of Medical Biochemistry, University of Wales, Cardiff
Contact Laboratory before requesting
Reference range
Reference ranges are age and sex dependent, please see report or contact lab.
Units
nmol/L
Turnaround Time
14
days
Department: Biochemistry
Clinical Application
Diagnosis and monitoring treatment in patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency. The test is also useful in investigation of hirsutism not due to polycystic ovary disease (a partial deficiency of the 21-hydroxylase enzyme can present in adult women)
NOTE: Blood spots can be used for monitoring known cases only, but plasma is required for urgent diagnosis. At least 2 blood spots taken onto ‘Guthrie’ filter cards. Allow to dry, put into polythene bag for posting. NB collect sample at least one day after birth.
Sequential measurement of 17-OHP as part of a short synacthen test (request 17-OHP as well as cortisol) is used in the investigation of suspected 21-hydroxylase deficiency where basal values are non-diagnostic.