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Alkaline Phosphatase - bone specific
minimum sample volume required ~ 5ml
Test Code: BSA
Tube type: SST
Special instructions
None
Reference range (adults)
Pre-menopausal women: 6.5 – 14.9
Males: 8.0 – 19.5
Levels are higher in children than in adults, by as much as 5-10 fold.
Post-menopausal reference ranges are poorly defined.
Sent away
to Charing Cross Hospital
Contact Laboratory before requesting
Units
IU/L
Turnaround Time
21
days
Department: Biochemistry
Clinical Application
The most useful application of bone specific ALP measurement is to monitor the response to anti-resorptive therapy in metabolic bone disease, eg. treatment of osteoporosis with oral alendronate therapy, or treatment of Paget’s disease with intravenous pamidronate. It is the marker of choice for the diagnosis and monitoring of Paget’s disease. A baseline pre-treatment sample is taken, followed by serial samples post-treatment, eg. after 3 and 6 months.
Please refer to Alkaline Phosphatase page for non bone specific ALP.
